Aside from the visual display, DecCor2 exploits the characteristics of the
distribution of gene expression vector similarities in order to output lists of
genes representing outliers in the distribution. This allows the easy creation
of lists of genes most strongly similar in their expression pattern to a gene of
interest. By specifying the number of standard deviations (SDs) away from
the mean of the distribution that a gene should be before being included in
an output list, the user has direct control over the inclusion parameter. Either
the distribution of gene-specifi c similarities (i.e., a gene-specifi c cutoff) or the
global distribution generated by considering all pairwise similarities (i.e., a
global cutoff) may be used.
Friday, April 10, 2009
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